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From community-based active surveillance data in Antelope Valley, California, (northeast of Los Angeles) from 1995-2004, 9.5% (1,080 subjects) of all 11,356 subjects with varicella had onset of rash > 42 days after varicella vaccination, which defines breakthrough varicella. The diagnosis was confirmed by physician evaluation or laboratory test in 770 subjects (71.3%).

Varicella Vaccine, Breakthrough Varicella, and Duration of Immunity