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These 2 clinical trials comparing Standard and New Antiepileptic Drugs (SANAD) showed that for partial epilepsy, lamotrigine was clinically better than carbamazepine, and that for generalized and unclassifiable epilepsy, valproate was better tolerated than topiramate and more efficacious than lamotrigine.

Which is Better, the Older or the Newer Antiepileptic Drugs?