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Synopsis: A large primary care pediatric study of recurrent urinary tract infections found a 12% per year recurrence rate with risk factors being white race, age 3-5 years, and grade 4-5 vesicoureteral reflux. Antimicrobial prophylaxis did not reduce the risk for recurrence but was associated with increased risk of recurrent infection caused by resistant organisms.

Prophylaxis for Recurrent UT Infections in Children