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In this largest reported series of surgical Stage I UPSC patients, recurrence rates were lower than those published in previous studies, suggesting a potential benefit of comprehensive surgical staging in these patients. The risk of recurrence and the mean overall survival were similar between surgical Stage I UPSC patients who were managed conservatively and those treated with adjuvant radiation therapy.

Uterine Papillary Serous Carcinoma: Comparisons of Outcomes in Surgical Stage I Patients With and Without Adjuvant Therapy