Small LDL particles linked to heart disease

Canadian investigators report that small low-density lipoprotein (LDL) particles appear to independently increase the risk of ischemic heart disease in men. At the University of Montreal’s Lipid Research Center in Quebec, researchers determined the LDL phenotype in a subgroup of men who had no clinical signs of ischemic heart disease, but developed it over the next five years. They compared those men with a matched control group who didn’t develop heart disease during that time. The presence of small, dense LDL particles was associated with an increase in the risk of heart disease, and men with those particles were more likely to have abnormal triglyceride, high-density lipoprotein, and other levels.

• April 5-6, Nutritional Approaches to Disease Prevention and Treatment — Sponsored by Harvard Medical School. Contact: Harvard Medical School CME, P.O. Box 825, Boston, MA 02117-0825. Telephone: (617) 432-1525. E-mail:

• April 12, Update Course on Alzheimer’s Disease and Other Dementias — Sponsored by the Johns Hopkins Medical Institutions (JHMI). Contact: JHMI, Office of CME, Turner 20, 720 Rutland Ave., Baltimore, MD 21205-2195. Telephone: (410) 955-2959. Fax: (410) 955-0807.

• April 17-18, Seventh Annual Clinical Care of the Patient with HIV Infection — Sponsored by JHMI. Contact: (see above).

• May 16-21, American Lung Association 1997 International Conference — Sponsored by American Lung Association (ALA). Contact: ALA/ATS, 1740 Broadway, New York, NY 10019-4374. Telephone: (212) 315-8700.

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