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Chronic fatigue syndrome (CFS) is common in community practice and it has been speculated that it is the result of chronic immune proliferation or infection. In a review of Surveillance, Epidemiology, and End Results registry data, coupled with Medicare claims data, an association of CFS with non-Hodgkin lymphoma is clearly demonstrated.

An Increased Risk of Non-Hodgkin Lymphoma in Chronic Fatigue Syndrome Patients