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Ninety-three percent of sputum isolates from a single long-term care facility were resistant to quinolones. Epidemiologic study showed an association with prior receipt of levofloxacin. Strains were closely related by pulsed field gel electrophoresis (PFGE) analysis, indicating patient to patient spread of a resistant clone.

An Outbreak of Quinolone Resistant Haemphilus influenzae in a Long-Term Care Facility