Skip to main content

All Access Subscription

Get unlimited access to our full publication and article library.

Get Access Now

Interested in Group Sales? Learn more

In a retrospective analysis of approximately 200 patients with early stage B-cell diffuse lymphoma, bone marrow aspirate and biopsy revealed involvement in only 3.6%. A review of a number of risk factors indicated 3 (low hemoglobin, low white blood count, and bulky disease) as predictors of marrow involvement. In fact, the absence of these 3 factors gave a negative predictive value of 99.2% for marrow involvement.

Rethinking Bone Marrows: Are They Necessary in Early Stage Diffuse B-Cell Lymphomas?