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Given the importance of acute bacterial rhinosinusitis (ABRS), a commonly encountered outpatient infection, this article attempts to outline in evidence-based detail what the authors conclude to be optimal, risk-stratified, empiric treatment recommendations. In addition, this review identifies key clinical findings, resistance patterns, risk factors, coexisting conditions, and other clinical triggers supporting referral of patients with ABRS to an otolaryngologist for more invasive — i.e., multimodal surgical and more intensive antimicrobial — management strategies.

Acute Bacterial Rhinosinusitis: Evidence-Based Management and Optimizing Antibiotic Therapy