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In an analysis of benign breast disease evaluated and treated within the Henry Ford Health system over a thirteen year period, the question of breast cancer risk was determined in the context of the number of benign breast lesions. Patient age and the histologic presence of "atypia" conferred increased risk of later breast cancer, as did the presence of multiple lesions, with or without histological "atypia" and when adjusted for age.

Multiplicity of Benign Breast Cancer Lesions: Risk for Progression to Cancer