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Statin drugs have been increasingly used for management of hypercholesterolemia. Preclinical studies indicated an antiproliferative effect in vitro and in rodent models of breast cancer. The current report is one of several that indicate a lack of evidence for reduction in breast cancer risk among statin users. However, the overall use of drugs in this class in the study cohort (7%) and the relatively short duration of use (approximately 4 years) suggest that the question is not completely resolved.

Statins and Breast Cancer: Yes, No, or Maybe