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    Home » Alzheimer_s

    Articles Tagged with ''Alzheimer_s''

    ABSTRACT & COMMENTARY

    Nutritional Interventions in Prodromal Alzheimer’s Disease: The 36-Month LipiDiDiet Multinutrient Clinical Trial

    November 23, 2020
    No Comments

    In a randomized, double-blind, placebo-controlled trial of Fortasyn Connect (Souvenaid), a nutraceutical drink, patients with prodromal Alzheimer’s disease demonstrated, over a 36-month period, a slower decline in cognitive functions compared to the control group.


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    ABSTRACT & COMMENTARY

    Fluctuating Cognition: An Often-Neglected Feature of Lewy Body Dementias

    December 17, 2019
    No Comments

    Clinical identification of fluctuating cognition is challenging. A better understanding of potential etiological mechanisms can allow for optimization of clinical assessment tools and targeted therapeutic approaches.


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    MONOGRAPH

    Dementia Update

    November 5, 2019
    No Comments

    Dementia is a common and growing problem that is associated with significant caregiver burden and immense cost. A growing focus on disease prevention and management of risk factors in mid-life is vital to attempt to mitigate the daunting impact of this illness on patients, caregivers, and the healthcare system as a whole.


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    ABSTRACT & COMMENTARY

    Tau PET Is Promising as a Diagnostic Agent in Chronic Traumatic Encephalopathy

    May 17, 2019
    No Comments

    Former NFL players with symptoms consistent with chronic traumatic encephalopathy had increased tau tracer uptake that was associated with years of playing football but not with cognitive or neuropsychological measures.


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    ABSTRACT & COMMENTARY

    Does Hormone Therapy Increase the Risk of Alzheimer’s Disease?

    May 8, 2019
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    A large Finnish case-control study suggests that postmenopausal hormone therapy results in a 9-17% increase in the risk of Alzheimer’s disease. However, the small effect size, and likely confounding of use effect, does not provide strong evidence for a causal relationship.


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    ABSTRACT & COMMENTARY

    Cholecystokinin as a Biomarker Linking Metabolic Function to Alzheimer’s Disease

    March 20, 2019
    No Comments

    In a study cohort from the Alzheimer’s Disease Neuroimaging Initiative, cerebrospinal fluid levels of cholecystokinin were associated with better outcomes that may reflect compensatory protection as Alzheimer’s disease pathology progresses. However, because of significant study limitations, these findings need to be validated in additional studies.


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    ABSTRACT & COMMENTARY

    Effect of Diet on Hippocampal Volume in a Population at Risk for Alzheimer’s Disease

    December 18, 2018
    No Comments

    Magnetic resonance imaging of the brain in community-dwelling people (average age of 60 years) found that a long-term, high-quality diet was associated with larger hippocampal volumes after an average interval of 11 years.


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    ABSTRACT & COMMENTARY

    Apolipoprotein E and CSF Levels in Men and Women With Alzheimer’s Disease

    December 14, 2018
    No Comments

    Apolipoprotein E epsilon 4 (APOE4) genotype, the stronger genetic risk factor for late-onset Alzheimer’s disease, negatively affects cerebrospinal levels of tau protein in a sex-dependent manner, whereby the effect of APOE4 is stronger in women than men.


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    ABSTRACT & COMMENTARY

    Effect of Diet on Hippocampal Volume in a Population at Risk for Alzheimer’s Disease

    October 19, 2018
    No Comments

    Magnetic resonance imaging of the brain in community-dwelling people (average age of 60 years) found that a long-term, high-quality diet was associated with larger hippocampal volumes after an average interval of 11 years.


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    ABSTRACT & COMMENTARY

    Predicting the Risk of Late-onset Alzheimer’s Disease and Dementia Based on Common Genetic Variants

    June 22, 2018
    No Comments

    Using a genetic risk score of 23 common genetic variants and apolipoprotein E genotype could help stratify individuals into those very likely to those very unlikely to develop late-onset Alzheimer’s disease and dementia.


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