Articles Tagged With: Biopsy
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MRI for the Evaluation of Inflammatory Myopathy
Magnetic resonance imaging (MRI) of large muscles is an important adjunctive diagnostic test for inflammatory myopathies, in conjunction with serum muscle enzymes and electrophysiology. MRI also can identify the highest-yielding section of muscle to target a muscle biopsy.
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CIN2 Is More Likely to Progress if HPV 16 Is Present
This study examined rates of cervical intraepithelial neoplasia grade 2 (CIN2) regression and progression among women ages 25-30 years and found that regression rates varied by human papillomavirus (HPV) genotype: 51% regression and 47% progression in HPV 16 infections compared to 83% regression and 16% progression for infections with other HPV types.
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Correlation of Electromyography With Pathology in Myopathy
A detailed analysis of electromyography features showed a high correlation with muscle pathology. However, pathologic changes on muscle biopsy may be present even with a totally normal electromyogram.
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Breast MRI Exams Increase the Biopsy Rate Without Improving Cancer Detection
Compared to women who undergo breast cancer screening with mammography alone, those receiving MRI exams experience a two- to fivefold increased rate of core and surgical biopsy. However, the biopsies have a lower cancer yield rate than mammography alone.
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Should Endocervical Curettage Be Performed Routinely During Colposcopy?
In this study, routine endocervical curettage (ECC) among women age 30 and older detected CIN 2 or worse in 14.4% of cases with higher likelihood of detection among women with high-grade squamous intraepithelial lesion, ASC-H, positive HPV 16 infection, or high grade colposcopic impression. The additional yield of ECC over lesion-directed ectocervical biopsies decreased with each additional biopsy.
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Who Needs an Endometrial Biopsy?
In this retrospective cohort study of premenopausal women with abnormal uterine bleeding, obesity, as opposed to age, was the most significant predictor of complex hyperplasia or cancer on endometrial biopsy.
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Diagnostic Concordance in Breast Biopsies
A comparison of breast biopsy diagnosis by clinical pathologists found a 75% concordance with a consensus-derived expert diagnostic interpretation. Concordance was lowest with the diagnosis of atypical, with under-diagnosis noted in 35% of cases.
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Sentinel Lymph Node Biopsy: What’s Ahead (and Neck) in Melanoma?