After an ischemic stroke of atherosclerotic origin, targeting low-density lipoprotein cholesterol to less than 70 mg/dL resulted in a significant reduction in subsequent major vascular events and no increase in intracranial hemorrhage.
These reviews of studies presented at the 2020 International Stroke Conference were written by Neurology Alert's editor after personal attendance at the presentations, followed by review of the simultaneous publications in Stroke. All comments and opinions are solely those of the editor.
Researchers found neither low levels of high-density lipoprotein nor high levels of low-density lipoprotein were associated with predicted survival in older women. This finding is consistent with other studies of cholesterol and mortality in the elderly.
The authors of this review of key nutritional studies compiled evidence-based information on foods and dietary patterns that support cardiovascular health and demystified those that have incorrectly been identified as beneficial to cardiovascular health.
Tsimané, a population living in the Bolivian Amazon, have the lowest prevalence of coronary artery disease among any population studied; individuals ≥ 40 years of age have mean low-density lipoprotein and high-density lipoprotein of 91 mg/dL and 39.5 mg/dL, respectively, despite a high inflammatory burden from parasites and pathogens.
In this randomized, double-blind study, patients with nonalcoholic steatohepatitis who received 2,700 mg of artichoke leaf extract (Cynara scolymus) or placebo daily for two months had a significant improvement in alanine aminotransferase and aspartate aminotransferase, as well as triglycerides and total cholesterol compared to the placebo group.