Articles Tagged With: Fluconazole
-
Ibrexafungerp for Vulvovaginal Candidiasis
A randomized clinical trial compared one day of oral ibrexafungerp with placebo for female patients with vulvovaginal candidiasis (VVC). It found ibrexafungerp to be safe and effective, with mild diarrhea the most common adverse event. Ibrexafungerp differs mechanistically from azoles and appears to be a promising new treatment for VVC.
-
Candida auris Resistant to Azole Antifungals, Amphotericin B, and Echinocandins
Infection with Candida auris resistant to azole antifungals, amphotericin B, and echinocandins was identified in three patients in New York. Resistance to echinocandins was first detected after the patients had received an echinocandin as treatment.
-
Prosthetic Valve Endocarditis Due to Candida
Prosthetic valve endocarditis due to Candida spp. is associated with high mortality, but is curable — or at least controllable.
-
Oral Fluconazole During Pregnancy Increases Risk for Spontaneous Abortion
A nationwide cohort study from Denmark found a significantly increased risk of spontaneous abortion associated with oral fluconazole usage. Caution with this medication during pregnancy is advised.
-
Fluconazole Use During Pregnancy
In this large cohort study from Denmark, use of oral fluconazole during pregnancy was associated with a slightly increased risk of spontaneous abortion and no increased risk of stillbirth.