Articles Tagged With: Leukemias
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Pediatric Oncology
Many emergency department (ED) visits for children are driven by parental fears of serious illness, including concerns that a child may have cancer. Some presenting symptoms are high-risk and require serious inquiry, while others are less concerning and may be managed by reassurance alone. Additionally, children with established cancer diagnoses may present to the ED with complications of their cancer, an unexpected recurrence after a period of remission, or issues related to treatment. The authors review the presentations for the most common pediatric cancers and the complications associated with pediatric cancers and their treatment.
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Acute Leukemia Patients Still Plagued by Vancomycin-Resistant Enterococci
Fifteen (7%) of 214 patients hospitalized with newly diagnosed acute leukemia developed bacteremia due to vancomycin-resistant enterococci; 12 (80%) of the 15 had stool colonization with the organism.
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Pharmacology Update: Nelarabine Injection (Arranon®)
The FDA has approved nelarabine for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and lymphoblastic leukemia (T-LBL). Nelarabine was approved under the FDAs accelerated approval program. It received an Orphan Designation because it is for a rare disease affecting less than 200,000 in the United States. Nelarabine is marketed by GlaxoSmithKline as Arranon®. -
Could Melphalan be Useful for Elderly Patients with Myelodysplastic Syndrome or Secondary Acute Myelogenous Leukemia?