Articles Tagged With: Lymphoma
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Defense Verdict Upheld Against Claims of Failure to Diagnose
This case can provide clinicians with an example and peace of mind knowing that appropriately abiding by the duties within their designated scope of practice is a method for defending against claims of malpractice.
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Long-Term Neurological Outcomes of Patients Treated with CAR-T Therapy
Chimeric antigen receptor (CAR)-T cell therapy is approved for the treatment of lymphoma, leukemia, and multiple myeloma, but its use is associated with early neurotoxicity in almost half of patients. Despite the incidence of neurotoxicity, long-term follow-up of patients after CAR-T infusion suggests that patients’ neurological examination, neuro-imaging studies, and cognition remain unaffected by this treatment.
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Treatment of Progressive Multifocal Leukoencephalopathy With Pembrolizumab
These authors evaluated the effect of pembrolizumab, a monoclonal antibody that functions as a down-regulator of PD-1 (programmed cell death protein 1), on patients with progressive multifocal leukoencephalopathy. In five of eight treated patients, clinical stabilization or improvement was seen in association with reduced cerebrospinal fluid JC viral load. This is the first reported effective treatment for this disease with a therapeutic agent targeting the JC virus.
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Treatment of Relapsing or Recalcitrant Cutaneous T-Cell Lymphoma with Pegylated Liposomal Doxorubicin