Articles Tagged With: Malaria
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Updated Management of Malaria
Malaria is preventable and treatable, yet there still are hundreds of millions of cases of malaria each year. New guidelines encourage personal and community prevention. Treatment usually is with artemisinin-based combination therapy.
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Treatment of Severe Plasmodium falciparum Malaria with Intravenous Artesunate
A prospective nationwide study in France found intravenous artesunate use was rapidly adopted by clinicians and was safe and highly effective in the treatment of severe malaria due to Plasmodium falciparum.
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Malaria in the United States
The number of cases of imported malaria in the United States continues to increase, with most cases caused by Plasmodium falciparum and most of the infections acquired in Africa, particularly West Africa. Almost three-fourths of U.S. residents with malaria had failed to take chemoprophylaxis and the remaining one-fourth often did not take recommended medications.
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Malaria: At Last a Vaccine
The World Health Organization has recommended the use of the first effective malaria vaccine.
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Infectious Disease Alert Updates
Pyrethroids losing activity against mosquitoes; Resistance erodes standard treatment for pneumonia; and homelessness and COVID-19.
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Emerging Options for Malaria Prevention
New data suggest that combining vaccination with chemoprophylaxis is better than either intervention alone, and a small pilot study suggests that a monoclonal antibody infusion is effective in preventing malaria infections.
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Pediatric Malaria
Malaria is present in all continents except Antarctica and has led to significant human illness and death. Children account for the majority of malaria deaths globally, making malaria a significant contributor to childhood mortality worldwide. Malaria is a mandatory consideration for children with fever who are returned travelers, since the disease process can lead to significant mortality and rapid clinical decline. The authors provide an update and current state of care for malaria in the pediatric population. -
Malaria: Look Beyond the Blood to the Spleen
The diagnosis of malaria depends on detection of the parasite, but the spleen is where the money is. -
Malaria and Anemia — Chemoprophylaxis Helps
For young children in Africa who return home after hospitalization for severe anemia, monthly long-acting malaria prophylaxis can reduce the rates of readmission and death during the three months following hospitalization.
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Malaria Prophylaxis During Pregnancy
In a retrospective study of American military women involving 50 treated with atovaquone-proguanil and 156 exposed to mefloquine, no increase in risk of fetal loss or adverse infant outcomes was identified. Atovaquone-proguanil seems safe for use in pregnancy, but data are limited.