Epileptic patients with major depression were randomized to either cognitive behavioral therapy (CBT) or sertraline. Depression and related secondary health outcomes were analyzed in both groups. Sertraline and CBT were found to be equally efficacious with improvement in mood in more than half of patients.
Epileptic patients with major depression were randomized to either cognitive behavioral therapy (CBT) or sertraline. Depression and related secondary health outcomes were analyzed in both groups. Sertraline and CBT were found to be equally efficacious with improvement in mood in just over one-half of the patients.
Epilepsy surgery is one of the treatment modalities for intractable pharmacoresistent epilepsy. For seizure freedom to be achieved, the epileptogenic zone (EZ) must be resected successfully. Stereoelectroencephalography is one of the invasive intracranial EEG recording techniques used for EZ localization. The technological advancements in the past two decades have made this procedure safer, more accurate, and easier to perform and therefore more readily available.
Juvenile myoclonic epilepsy (JME) is a common form of generalized epilepsy. Although the prognosis of JME is not clear, it is assumed to have a good response to treatment. The authors of this meta-analysis found a higher than expected prevalence of refractoriness in JME, which will affect how neurologists counsel patients with JME.
These investigators found that adding witness-reported observations to patient demographics and patient-reported symptoms improved the diagnostic accuracy between epilepsy, syncope, and psychogenic nonepileptic seizures.
In an analysis of insurance claims for 1.8 million U.S. children with 2,950 recorded seizures, researchers found that the risk of hospitalization for seizures was 24% lower in rotavirus-vaccinated children.
In a review of 377 magnetoencephalography (MEG) studies in epilepsy patients undergoing presurgical workup, 44 patients were found to have one or more seizures during routine recordings, lasting up to a mean of 51.2 minutes. Ictal MEG provided unique localizing data in about one-third of patients. For patients with frequent seizures or reliably induced seizures, MEG may be a useful supplemental tool for medically refractory epilepsy patients undergoing presurgical evaluation.
Understanding the potential reactions that can occur from cannabis and synthetic cannabinoids can help emergency physicians recognize these effects in patients who may present to the emergency department.