Articles Tagged With: Seizures
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Epilepsy Management
Epilepsy affects about 50 million people worldwide and is responsible for up to 0.5% of the global burden of disease. Although many people learn to handle their epilepsy at home, patients often are brought to the emergency department if they have a seizure in public or it is their first seizure.
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Intravenous Immunoglobulin for Treatment of Autoimmune Epilepsies
Patients with LGI1 and CASPR2 IgG-associated autoimmune epilepsy were identified and randomized to treatment with intravenous immunoglobulin (IVIG) vs. placebo. The authors hypothesized that IVIG would show superiority over placebo, with a primary endpoint of 50% or greater seizure reduction.
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Status Epilepticus
Status epilepticus is a serious medical condition that is defined as a seizure lasting longer than five minutes or more than one seizure without recovery to baseline between seizures.
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Epilepsy Management in Primary Care
Epilepsy affects about 50 million people worldwide and is responsible for up to 0.5% of the global burden of disease. There are more than 5 million people diagnosed with epilepsy every year and that number is expected to continue to rise.
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Status Epilepticus
The authors present an approach to the diagnostic evaluation and therapeutic management of neonates and children in SE.
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Treating Depression in Epilepsy: To Medicate or Not?
Epileptic patients with major depression were randomized to either cognitive behavioral therapy (CBT) or sertraline. Depression and related secondary health outcomes were analyzed in both groups. Sertraline and CBT were found to be equally efficacious with improvement in mood in more than half of patients.
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Treating Depression in Epilepsy: To Medicate or Not?
Epileptic patients with major depression were randomized to either cognitive behavioral therapy (CBT) or sertraline. Depression and related secondary health outcomes were analyzed in both groups. Sertraline and CBT were found to be equally efficacious with improvement in mood in just over one-half of the patients.
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Stereoelectroencephalography in Surgical Evaluation of Intractable Epilepsy
Epilepsy surgery is one of the treatment modalities for intractable pharmacoresistent epilepsy. For seizure freedom to be achieved, the epileptogenic zone (EZ) must be resected successfully. Stereoelectroencephalography is one of the invasive intracranial EEG recording techniques used for EZ localization. The technological advancements in the past two decades have made this procedure safer, more accurate, and easier to perform and therefore more readily available.
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Ketogenic Diet for Refractory Pediatric Seizures
This retrospective study of 59 children with refractory seizures of genetic etiology investigates the impact of a strict low-carb diet (either modified Atkins or ketogenic diet) on seizure reduction.
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Prevalence of Refractory Juvenile Myoclonic Epilepsy
Juvenile myoclonic epilepsy (JME) is a common form of generalized epilepsy. Although the prognosis of JME is not clear, it is assumed to have a good response to treatment. The authors of this meta-analysis found a higher than expected prevalence of refractoriness in JME, which will affect how neurologists counsel patients with JME.