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Articles Tagged With: acute

  • Acute Small Fiber Neuropathy

    Acute-onset small fiber neuropathy most often is precipitated by infections, medication side effects, or vaccinations. Most cases recover spontaneously.

  • A Comparison of Acute Migraine Therapies Using Big Data

    In a big data-driven observational study that compared 3 million treated migraine attacks captured from a migraine diary smartphone app, triptans were found to be the most efficacious treatment class. Among the triptans, eletriptan had the highest rate of success. Consistent with clinical practice and recent consensus statements, the success of triptans was followed by ergots and antiemetics.

  • Decompressive Craniectomy for Acute Subdural Hematoma

    There has been longstanding discussion about whether craniectomy results in better outcomes than craniotomy with preservation of the skull for treatment of patients with acute subdural hematomas. This multicenter, international clinical trial was designed to compare the long-term results, benefits, and complications of decompressive craniectomy vs. craniotomy in patients with acute subdural hematomas.

  • Benefits and Risks of Dual Antiplatelet Therapy After Acute Ischemic Stroke or TIA

    Secondary prevention of acute ischemic stroke is continuing to evolve with great interest in the use of dual antiplatelet treatment early in the course. A complicating factor has been the role of the CYP2C19 loss-of-function gene that interferes with the conversion of clopidogrel to its active antiplatelet metabolite.

  • Treatment of Acute Vertigo

    In a meta-analysis of published studies of treatment of acute vertigo, the authors concluded that treatment with an antihistamine is more effective than benzodiazepines for the acute symptoms. However, there was no difference between the two medications in terms of resolution within one week or within one month.

  • Surge of HIV Patients Present to EDs, Leaders Call for Expanded Screening

    Investigators discovered a more than twofold increase in cases of acute HIV during the COVID-19 pandemic as part of an ED-based screening program at UChicago Medicine. The cause of the increase remains unknown, but it underscores the importance of screening despite the fact the pandemic has strained all resources.

  • Long COVID: The Daunting Aftermath of Even Mild Infections

    One of the most mysterious and disturbing aspects of SARS-CoV-2 infection is so-called “long COVID,” which presents as a panoply of symptoms that can linger for months after even mild acute cases.

  • Ticagrelor Added to Aspirin Reduces Long-Term Risk of Recurrent Stroke or Death After Ischemic Stroke or TIAs

    The Acute Stroke or Transient Ischemic Attack Treated with Ticagrelor and ASA for Prevention of Stroke and Death (THALES) study was designed to test the hypothesis that 30-day treatment with ticagrelor and aspirin would be superior to aspirin alone in reducing the risk of subsequent stroke or death in patients who had a non-cardioembolic ischemic stroke or transient ischemic attack.

  • Mobile Stroke Units: What Is the Best Way to Use Them?

    A recent advance in ischemic stroke treatment is the mobile stroke unit, an ambulance outfitted with specialized equipment, computed tomography for brain imaging, and a specialized team with a stroke neurologist available either onboard or via telemedicine. Intravenous thrombolytics can be administered at the scene with the patient on the ambulance.

  • Pain Management in the Emergency Department: Opioids and Alternative Pain Management Therapies

    Opioid therapy can be an effective form of pain management in the ED for acute painful conditions. The risk of addiction and abuse should be considered in every case. Alternatives to opioid therapy include systemic agents, such as acetaminophen, NSAIDs, lidocaine, alpha agonists, anticonvulsants, ketamine, corticosteroids, and local and regional anesthesia.