Articles Tagged With: als
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Early Respiratory Decline in Amyotrophic Lateral Sclerosis
Hypercapnia, a manifestation of early respiratory dysfunction, can be challenging to detect in amyotrophic lateral sclerosis (ALS) patients. Pulmonary function tests are helpful, but their specificity in detecting hypercapnia is low and their use is limited in patients with bulbar weakness. Specific symptoms, such as dyspnea at rest, dyspnea while talking, and use of medications for sleep, can be more reliable in detecting hypercapnia among ALS patients.
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Patterns of Weakness in Amyotrophic Lateral Sclerosis
Unusual patterns of weakness in the various motor neuron disorders may point to a specific diagnosis of amyotrophic lateral sclerosis, if supported by electrophysiological evidence of chronic denervation.
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Systemic Immune Activation and the Course of Amyotrophic Lateral Sclerosis
Activation of the immune system has been recognized in patients with amyotrophic lateral sclerosis, and immune activation may influence the course of the disease and the speed of progression.