Articles Tagged With: antibiotics
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Do Antibiotics Reduce Hormonal Contraceptive Effectiveness?
This is a systematic review of studies evaluating the effect of concomitant non-rifamycin antibiotic use on hormonal contraceptive effectiveness. Although data are limited, there is no evidence to support the existence of drug interactions.
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Microbiology of Hidradenitis Suppurativa: New Evidence That Anaerobes Predominate
Using metagenomic techniques, investigators determined that two Gram-negative anaerobes, Prevotella and Porphyromonas, predominate in hidradenitis suppurativa lesions. Two others, Fusobacterium and Parvimonas, correlate with disease severity.
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Skin and Soft Tissue Infections
Skin and soft tissue infections are encountered commonly in the emergency department, presenting as a range of disorders, from uncomplicated cellulitis, impetigo, folliculitis, erysipelas, and focal abscesses to necrotizing fasciitis.
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Dual Antibiotic Therapy Is Not Routinely Necessary for Uncomplicated Cellulitis
A randomized, multicenter, placebo-controlled clinical trial that enrolled patients presenting to emergency departments with uncomplicated cellulitis found the addition of trimethoprim-sulfamethoxazole to cephalexin did not lead to better outcomes.
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Evaluation and Management of Abscesses in the Emergency Department
This article reviews the current management options for simple cutaneous abscesses in patients, including review of the epidemiology, differential diagnosis, diagnostic studies, and changing practice of wound cultures and antibiotic therapy.
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Discharge Antibiotic Prescriptions Often Are Inappropriate with Regard to Choice, Dose, Duration
Seventy percent of discharge antibiotic prescriptions are inappropriate.
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Ventilator-associated Pneumonia with Minimal Ventilatory Requirements — Discontinuing Antibiotics After Three Days
Discontinuation of empiric antibiotic therapy given for treatment of presumed ventilator-associated pneumonia can be discontinued safely after three days in patients with minimal ventilator requirements.
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A Short Course of Antibiotics for Acute Otitis Media in Children Leads to Worse Outcomes Compared to Standard Course Therapy
A randomized, placebo-controlled clinical trial determined that in children 6-23 months of age with acute otitis media, five days of amoxicillin-clavulanate resulted in more clinical failure compared to a 10-day course of therapy.
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Antibiotic Stewardship in Outpatient Settings
The implementation of antibiotic stewardship principles in all outpatient settings is crucial to the struggle against growing antimicrobial resistance and to optimal patient outcomes.
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FDA Is Approving New Antibiotics — But Is the Result Just Higher Prices for More of the Same?
Eight new antibiotics received FDA approval from 2010-2015.