Articles Tagged With: antibiotics
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Prevent the Bug, Save the Drug:
Once largely consigned to separate silos, infection prevention and antibiotic stewardship are starting to show signs of a powerful partnership. The CDC’s most recent update on the threat of antibiotic-resistant bacteria emphasizes that drug stewardship and infection control must essentially be inseparable if they are going to be successful.
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Antibiotics over surgery for peds appendicitis? Proceed with caution, experts say
Several recent studies suggesting that appendicitis could be treated with antibiotics alone have generated serious buzz among clinicians and parents.
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Antibiotic Therapy for Pediatric Parapneumonic Empyema
In a retrospective review of 391 children with parapneumonic empyema, the safety and effectiveness of oral antibiotic therapy was comparable to outpatient parenteral antibiotic therapy for antibiotic management following hospitalization.
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Does Bacteremia Associated with Bone and Joint Infections Require Prolonged IV Antibiotic Therapy?
Two hundred sixty-five children with culture-proven acute bone or joint infections were studied. All patients received 2-4 days of IV antibiotics followed by PO antibiotics. Clinical outcomes and resolution of inflammatory biomarkers were the same whether the patient had positive blood cultures or not on admission.
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Antibiotics for Acute Appendicitis
ABSTRACT & COMMENTARY: Of those who needed surgery after treatment with antibiotics, the risk for complications was low.
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Antibiotics for Intraabdominal Infections: Less Is More
A multi-center, randomized trial comparing patients with complicated intraabdominal infections found no difference in outcomes between those who received 4 days of antibiotic therapy vs. 8 days after adequate source control.
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Duration of Antibiotic Treatment for Vertebral Osteomyelitis
Three hundred fifty-nine patients with pyogenic vertebral osteomyelitis were randomized to 6 weeks vs. 12 weeks of antibiotic treatment in an open-label controlled trial. Six weeks of antibiotics was found to be not inferior to 12 weeks of treatment.
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Nasal Screening for MRSA: The New Basis for De-escalation of Empiric Antibiotics?
The high negative predictive value of a negative nasal screen for methicillin-resistant Staphylococcus aureus suggests these patients do not have lower respiratory tract infections caused by the organism.
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Computer Decision Support for Antibiotic Prescribing
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Once Daily Oral Ofloxacin in COPD Exacerbation Requiring Mechanical Ventilation