Articles Tagged With: antibiotics
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What Is the Optimal Duration of Antibiotics for a Complicated UTI with Bacteremia?
An observational study of adults hospitalized with a complicated urinary tract infection and bacteremia revealed seven days of therapy was enough for most cases when they received antibiotics with comparable intravenous and oral bioavailability.
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What Is the Optimal Duration of Antibiotics for a Complicated UTI with Bacteremia?
An observational study of adults hospitalized with a complicated urinary tract infection and bacteremia found seven days of therapy was enough for the majority of cases when they received antibiotics with comparable intravenous and oral bioavailability.
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Scientists Use Artificial Intelligence While Searching for ‘Superbug’ Solutions
Researchers enlisted the help of technology to find an antibiotic that could fight multidrug-resistant bacteria.
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Inappropriate Antibiotic Prescribing Is Common for Elective Surgeries
A retrospective cohort study of adults who underwent an elective craniotomy, hip replacement, knee replacement, spinal procedure, or hernia repair revealed only 59% adhered to recommended guidelines on prophylactic antibiotic prescribing. Unnecessary vancomycin use was the most common reason for nonadherence and had 19 times higher risk for acute kidney injury.
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Antibacterial Therapy in the Critically Ill
Appropriate antibiotic therapy in the critically ill requires consideration of important patient-specific factors, such as antibiotic therapy in the preceding 30 days; culture and sensitivity data, if available, within the prior six months; and local resistance patterns.
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A Rapid Molecular Test Improves Time to Appropriate Therapy and Mortality in Patients with CRE Bacteremia
A multicenter observational study of patients with carbapenem-resistant Enterobacterales bacteremia found that time to receipt of active antibiotic therapy and mortality were improved in those whose blood cultures underwent rapid molecular testing for the Klebsiella pneumoniae carbapenemase gene. The mortality rate was 10% with ceftazidime-avibactam compared to 31% with polymyxin monotherapy.
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Comparison of Postoperative Antibiotic Regimens for Complex Appendicitis: Is Two Days as Good as Five Days?
In a pragmatic, open-label, randomized trial conducted at 15 hospitals in the Netherlands, two days of postoperative intravenous antibiotics for complex appendicitis was found to be noninferior to five days in terms of infectious complications and mortality within 90 days.
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A Comparison of Ceftaroline and Daptomycin in the Treatment of MRSA Bloodstream Infections
Ceftaroline is an acceptable alternative therapy for treatment of methicillin-resistant Staphylococcus aureus bacteremia.
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Antibiotic Resistance: We Were Doing Great and then COVID Happened
After improvement, antimicrobial resistance in the United States significantly increased.
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Macrolides and Hearing Loss — A Risk for Children?
In a large U.S. population group, use of short-term oral azithromycin was associated with an increased risk of sensorineural hearing loss.