Articles Tagged With: antibodies
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Misdiagnosis of Autoimmune Encephalitis
A recent multicenter, retrospective review of 393 adult patients given a diagnosis of autoimmune encephalitis noted that 107 patients (27%) were misdiagnosed and ultimately had other diagnoses confirmed, but after a considerable delay.
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Can Maternal COVID-19 Vaccination Protect Newborns?
In this case control study, 537 case infants younger than 6 months of age who were admitted to the hospital with COVID-19 were compared to 512 control infants who were hospitalized for other reasons; 16% of the case infants and 29% of the control infants had been born to mothers who had been fully vaccinated against COVID-19 during the pregnancy. The effectiveness of maternal vaccination against infant hospitalization for COVID-19 was 52% overall, 80% during the Delta variant period, and 38% during the Omicron variant period. Effectiveness increased when the vaccine was received after 20 weeks of pregnancy.
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Too Many Antibiotics May Affect Vaccine Response Among Infants, Toddlers
Remain cautious about overprescribing antibiotics.
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Reinfection: COVID-19 Vaccine Twice as Effective as Antibodies
COVID-19 vaccination is more than twice as protective as circulating antibodies in people who had a prior infection with SARS-CoV-2, the Centers for Disease Control and Prevention reports.
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Healthcare Workers with COVID-19 Antibodies: Strong Protection Against Reinfection
A study of healthcare workers demonstrated the presence of antibody to SARS-CoV-2 spike protein or to nucleocapsid provides strong protection against infection for up to six months.
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Vaccines Threatened, Still Effective Against COVID-19 Variants
Current vaccines are holding against an emerging array of highly transmissible SARS-COV-2 variant strains, but researchers are warning that a somewhat literal “arms race” has begun between immunization science and relentless evolution.
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Management of Pulmonary-Renal Syndrome
The role of the intensivist in the management of pulmonary-renal syndrome includes appropriate respiratory support and recognition and management of concurrent infection, hypovolemia, acute anemia, and coagulopathy.
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COVID-19 Mutations not Expected to Elude Vaccine
Despite the unknowns, veteran researchers and epidemiologists are expressing fairly high confidence that a vaccine against SARS-CoV-2 will be developed.
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Dermatomyositis Sine Dermatitis Is an Important Clinical Entity
Dermatomyositis is an autoimmune disorder of skeletal muscle associated with a variety of auto-antibodies and specific muscle pathology but it may not have a skin rash. Muscle pathology and antibody determinations are important for accurate diagnosis and treatment.
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Repeat Infections with Endemic Coronaviruses and Possible Implications for COVID-19
Repeat infection with endemic seasonal coronavirus occurs commonly and raises concerns about immunity to SARS-CoV-2 as well as about the efficacy of vaccines in the protection against infection due to this virus.