Articles Tagged With: artery
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Tenecteplase vs. Alteplase for Thrombolysis in Basilar Artery Occlusion
Basilar artery occlusion is a dangerous clinical syndrome of large artery occlusion that carries a high morbidity and mortality with severe disability in survivors. In multiple trials, alteplase has shown minimal benefit in achieving reperfusion in patients with large artery occlusion, including the basilar artery. Tenecteplase is a modified variant of alteplase that has greater specificity in binding to fibrin, a longer half-life, and can be administered in a single bolus.
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Medical Therapy vs. Carotid Endarterectomy in Patients with Asymptomatic Carotid Stenosis
Since the pivotal trials demonstrating the benefit of endarterectomy vs. medical therapy many years ago, there has been significant improvement in the risk factors for atherosclerosis, including better treatment of blood pressure and diabetes, as well as improved antiplatelet medication regimens and high-potency statins.
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Arterial Ischemic Stroke Prevention and Risk Factor Management
Stroke prevention is complex because of the varied stroke etiologies and the multifactorial approach necessary for optimal stroke prevention and risk factor management. Inevitably, primary care providers will be part of every aspect of stroke care and, with a thorough understanding of key aspects, can greatly assist in the management of these patients.
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Treatment of Central Retinal Artery Occlusion with Intravenous Thrombolysis
Central retinal artery occlusion is a serious threat to vision caused by interruption of the blood supply to the retina and leading to sudden, painless loss of vision in one eye. For 30 years there have been anecdotal reports and small case series suggesting that intravenous thrombolysis might be beneficial in this disorder, but none of the stroke treatment guidelines have incorporated thrombolysis as definitive treatment for this disorder.
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Endovascular Treatment for Acute Basilar Artery Occlusion Is Safe and Effective
Patients with acute basilar artery occlusion treated by endovascular therapy within 24 hours of occlusion time had better functional outcomes and reduced mortality compared to those treated with medical therapy alone.
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Stroke: The Subtle, Atypical, and Enigmatic
This article will explore the subtle and enigmatic presentations of stroke. These patients often will present with nonspecific symptoms, such as vision problems, headache, a subtle language deficit, dizziness, or amnesia.
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Transient Ischemic Attack
Recent research on transient ischemic attacks (TIA) has changed how emergency medicine providers evaluate and manage this sometimes difficult diagnosis. This article provides readers with current information and relevant studies pertaining to TIAs.
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Acute Ischemic Stroke Due to Large Vessel Occlusion
Acute stroke reperfusion therapies have led to significant reduction in the morbidity and mortality associated with ischemic strokes due to large vessel occlusion. This article will discuss the prevalence, mechanism, diagnosis, and treatment options of acute ischemic stroke due to large vessel occlusion.
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Basilar Artery Thrombectomy Can Be Accomplished with Acceptable Outcomes
A recent study found that mechanical thrombectomy for basilar artery occlusion can be accomplished with a similar success rate as that which has been published in large multicenter, randomized trials of thrombectomy.
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Evaluation and Management of Cervical Artery Dissection in the Emergency Department
The goal of this paper is to help emergency physicians in their diagnosis, management, and treatment of this rare but potentially devastating condition.