In this randomized, double-blind, controlled trial, routine treatment with metronidazole compared to placebo in addition to doxycycline and ceftriaxone reduced the presence of endometrial anaerobes, Mycoplasma genitalium, and pelvic tenderness at 30 days post-treatment. However, clinical improvement at three days post-treatment was no different between the two groups.
Although showering with hot water and harsh soap daily may not be optimal, studies have shown that regular bathing with good soap and water reduces the risk of infection in individuals colonized with Staphylococcus aureus.
Researchers analyzed the diagnostic accuracy and yield of sputum Gram stain (SGS) in community-acquired pneumonia across 24 studies of 4,533 adult patients in a meta-analysis. SGS was specific for the diagnosis of Streptococcus pneumoniae and Haemophilus influenzae infection.
Challenges remain, but programs in place at most hospitals
September 18, 2019
Infection preventionists (IPs) are playing key roles in antibiotic stewardship programs, which are now in place in most U.S. hospitals and making some hard-earned progress against a horde of multidrug-resistant bacteria.
Researchers are exploring the use of metronidazole for the treatment of endometriosis, which affects up to 10% of U.S. women between the ages of 25 and 40. The current treatment options include hormone therapy and surgery, but these approaches involve significant side effects and recurrence of the condition after treatment.
Tachypnea has long been considered to identify which children with acute fever and cough might benefit from antibiotic treatment, especially in resource-limited parts of the world. Now, with declining rates of vaccine-preventable infections with Haemophilus influenzae and pneumococcus, new data suggest that approximately 90% of febrile, tachypneic, coughing (but still well enough for outpatient treatment) preschoolers do fine without antibiotics.