Women’s health benefits from waiting at least two years after a live birth before the next pregnancy. The results of a recent study reveal that women are more likely to space out childbearing after participating in a two-year intervention that includes providing women with access to family planning counselors, free transportation to a high-quality family planning clinic, referrals for services, consultations, and financial reimbursement for family planning services.
In this population-based cohort study of 1,027 infants born to women treated with anti-TNF-α biologic therapy, there was an increased prevalence of preterm birth (adjusted odds ratio [aOR], 1.61; 95% confidence interval [CI], 1.29-2.02), cesarean delivery (aOR, 1.57; 95% CI, 1.35-1.82), and small for gestational age neonates (aOR, 1.36; 95% CI, 0.96-1.92) when treatment with anti-TNF was compared to non-biologic systemic treatment. Since disease processes varied greatly in these pregnant women, it was difficult to rule out confounding by disease severity (confounding by indication).
In this case control study using U.S. live birth records between 22 and 23 weeks of gestation, maternal intervention was positively associated with increasing maternal age, Medicaid use, preeclampsia, birth defects, twin gestation, multiparity, and infertility treatments while being negatively associated with non-Hispanic Black race. Positive associations for neonatal intervention included non-Hispanic Black race, preeclampsia, Medicaid use, infertility treatments, less than a high school education, increasing maternal age, and twin gestation, and negative associations included birth defects and small for gestational age pregnancies.
In this open-label, equivalence randomized trial of vaginal progestogen compared to intramuscular progestogens for preventing preterm birth in high-risk women, the difference in the risk of preterm birth at < 37 weeks of gestation between both groups was 3.1% (95% confidence interval, -7.6% to 13.8%), which was within the equivalence margin of 15% used in the study.
American women who are pregnant or have just given birth are dying at a rate higher than most high-resource nations, and the morbidity rate is three to four times greater for black women. Their death rate is equivalent to pregnant women in less affluent nations, including Mexico or Uzbekistan. Maternity case managers can help prevent pregnant women from experiencing health crises and help keep their infants out of the neonatal ICU. Case management helps promote better education about the risks of preterm births.
In a multicenter, randomized clinical trial, researchers found that a single dose of intravenous amoxicillin/clavulanic acid significantly reduced the risk of infection following operative vaginal birth (forceps or vacuum extraction) compared to placebo (180 of 1,619 [11%] vs. 306 of 1,606 [19%], respectively; P < 0.0001).
Scientists at Brigham and Women’s Hospital have published early results of an investigative blood test designed to predict which women may be at increased risk and which ones may be at lower-than-average risk for spontaneous preterm delivery. The researchers have identified circulating microparticle proteins found in blood samples taken in the first trimester of pregnancy that may provide clues about the risk of spontaneous preterm birth.
In new research, investigators analyzed the risk of preterm birth among women with a previous poor pregnancy outcome. The results indicated that women had a higher chance of delivering before 32 weeks if their previous infant was born small for its gestational age. Those with a previous neonatal death were three times as likely to have a preterm birth subsequently, data indicated.