Deep brain stimulation can be a treatment option for refractory obsessive-compulsive disorder, but the results are not significantly better than lesioning procedures. Small sample sizes, diverse targets of stimulation, and inconsistencies in rating scales are limiting factors in the studies of this modality.
Epilepsy affects about 50 million people worldwide and is responsible for up to 0.5% of the global burden of disease. Although many people learn to handle their epilepsy at home, patients often are brought to the emergency department if they have a seizure in public or it is their first seizure.
A cohort study assessing participants from the Professional Fighters Brain Health Study found that the presence of cavum septum pellucidum and cavum vergae is associated with lower regional brain volumes and lower cognitive performance.
Epilepsy affects about 50 million people worldwide and is responsible for up to 0.5% of the global burden of disease. There are more than 5 million people diagnosed with epilepsy every year and that number is expected to continue to rise.
The authors of a cross-sectional study involving analysis of data from the ongoing Understanding Neurologic Injury and Traumatic Encephalopathy (UNITE) study found that dementia is likely a result of neuropathologic changes associated with repetitive head injury as well as non-head trauma-associated vascular pathologic changes in patients with chronic traumatic encephalopathy.
Media coverage of professional athletes experiencing irreversible damage after repeated brain trauma and of the underreported rates and risks of pediatric concussion have heightened awareness surrounding head injury in sports and recreation. Concussion is now known to be a significant public health issue, with high rates of emergency department visits and hospitalizations. Much of the current concern surrounding concussions revolves around recognition, early diagnosis, treatment modalities, return-to-play, and prevention of recurrent concussions.
In this prospective longitudinal study investigating the potential mechanistic link between adiposity and vascular cognitive impairment, anthropometric and metabolic hormone adiposity predictors were differentially associated with cerebrovascular and brain volumetry outcomes by sex in older individuals.
Organ donation and transplantation are important and lifesaving procedures.The complexities of management include determination of death, communication with families, pre-procurement optimization of potential donors, and bereavement support for families.