Articles Tagged With: candida
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Rezafungin Injection (Rezzayo)
Rezafungin can be prescribed to treat candidemia and invasive candidiasis in patients age 18 years or older with limited or no alternative options.
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Candida Endocarditis
A review of a national administrative database examined 703 patients with Candida endocarditis and found the greatest risk factor for mortality was underlying liver failure, while a history of opiate abuse was associated with a reduced risk of death.
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Candidemia in the United States
Candidemia, a common bloodstream infection in the United States, is associated with high mortality. There is concern about increasing resistance to antifungals.
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Candida auris Resistant to Azole Antifungals, Amphotericin B, and Echinocandins
Infection with Candida auris resistant to azole antifungals, amphotericin B, and echinocandins was identified in three patients in New York. Resistance to echinocandins was first detected after the patients had received an echinocandin as treatment.
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C. auris: A Bad Bug With a Worst-Case Scenario
Imagine if a common healthcare-associated infection became impossible to treat. The nightmare scenario public health officials are contemplating is that an emerging strain of multidrug-resistant Candida auris will displace treatable strains of Candida, which are already a leading cause of bloodstream infections.
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Murderers’ Row: Resistant to Drugs, Threats to Humans
In a recently published report on antibiotic threats in the United States, the Centers for Disease Control and Prevention classified pathogens as urgent, serious, concerning, or put them on a “watch list.”
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Isavuconazole vs. Caspofungin for Candidemia
In a large, randomized, double-blind, multicenter clinical trial, researchers found that isavuconazole did not meet the primary endpoint of noninferiority compared to caspofungin for candidemia and invasive candidiasis.
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Infectious Disease Alert Updates
Worse Than Snake Oil; Contract Tracing Using WHO Network; Preparing Your Hospital for Candida auris
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Prosthetic Valve Endocarditis Due to Candida
Prosthetic valve endocarditis due to Candida spp. is associated with high mortality, but is curable — or at least controllable.
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Fungal Endophthalmitis: Another Risk Associated With Intravenous Drug Use
A retrospective cohort study found that endogenous fungal endophthalmitis is associated with intravenous drug use and frequently results in poor visual outcomes despite appropriate surgical and antifungal therapy.