A population-based cohort study showed that exposure to antibiotics during the first two years of life is associated with increased rates of subsequently developing asthma, allergic rhinitis, atopic dermatitis, attention deficit hyperactivity disorder, celiac disease, and obesity.
This prospective United Kingdom study involving 13,488 children shows an association between specific early childhood sleep problems and symptoms of psychosis in adolescence. Another specified early childhood sleep problem is associated with symptoms of borderline personality disorder in adolescence.
Each year, 30 million preschool-aged children still get sick with diarrhea and 330,000 die. Most diarrheal illness and death is concentrated in a few high-risk areas, including parts of Benin, Lesotho, Mali, Nigeria, and Sierra Leone. Targeting preventive and therapeutic interventions in areas of risk could markedly reduce morbidity and mortality.
Long-term symptoms and disability from chemotherapy-induced peripheral neuropathy occur in more than half of childhood survivors of cancer, with vinca alkaloids and platinum agents implicated most often.
In a large population-based study, antibiotic use during the first six months of life was associated with a two-fold increase in asthma and a 1.5-fold increase in allergic disease during early childhood.
A large study that reviewed longitudinally collected data from the national Swedish Patient Register found that head trauma in adolescents was associated with an increased risk of subsequent diagnosis of multiple sclerosis.