Cilostazol is a phosphodiesterase 3 inhibitor widely used in Asia for secondary stroke prevention but approved for use in North America only for symptomatic peripheral vascular disease. It has been theorized that cilostazol might be beneficial in preventing the progression of small vessel disease in the brain and, therefore, may have a secondary effect in preventing vascular dementia.
Healthcare workers and patients who have contracted SARS-CoV-2, particularly if they were hospitalized, could be at risk of neurological deficits in the short term and as well as later cognitive problems.
Young women with depression experience a higher rate of unintended pregnancy and sexually transmitted infections than young women, in general. The challenge for family planning clinicians is to find an effective intervention to help them prevent pregnancy and maintain their health.
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women. Women who initiated estrogen therapy early (within five years of the onset of menopause) showed higher cognitive test scores than those who started later.
There is no mandatory retirement age for physicians, but there is good reason to consider how aging may affect their abilities to safely and effectively practice medicine, especially for surgeons. Some healthcare organizations are addressing those concerns with programs that provide additional monitoring and testing for physicians as they age.
A cohort study assessing participants from the Professional Fighters Brain Health Study found that the presence of cavum septum pellucidum and cavum vergae is associated with lower regional brain volumes and lower cognitive performance.
Clinical identification of fluctuating cognition is challenging. A better understanding of potential etiological mechanisms can allow for optimization of clinical assessment tools and targeted therapeutic approaches.
Dementia is a common and growing problem that is associated with significant caregiver burden and immense cost. A growing focus on disease prevention and management of risk factors in mid-life is vital to attempt to mitigate the daunting impact of this illness on patients, caregivers, and the healthcare system as a whole.