Articles Tagged With: dexmedetomidine
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Dexmedetomidine Sublingual Film (Igalmi)
Dexmedetomidine can be prescribed for the acute management of agitation associated with schizophrenia or bipolar I or II disorder.
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Dexmedetomidine for Sedation in Patients Undergoing Mechanical Ventilation in the ICU
This special feature will focus on dexmedetomidine as a sedative for invasive mechanical ventilation in the ICU.
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Dexmedetomidine and Temperature Elevation: Is the Link Important?
In this post hoc analysis of the SPICE III trial, a greater percentage of patients receiving dexmedetomidine had temperatures greater than or equal to 38.3ºC and 39.0ºC compared to usual care. Although there was a significant dose response relationship between dexmedetomidine received and increase in temperature, there was no difference between groups in terms of paracetamol, antimicrobial, neuromuscular blocker, neuroleptic drug use, blood cultures performed, or initiation of renal replacement therapy. -
Dexmedetomidine Compared to Propofol for Sedation in Mechanically Ventilated Patients with Sepsis
The MENDS2 trial found that dexmedetomidine, when used for light sedation, had outcomes similar to those for propofol. -
Early Dexmedetomidine Provides Similar 90-Day Mortality Compared to Usual Care in Mechanically Ventilated Critically Ill Adults
When the early use of continuous infusion dexmedetomidine was compared to usual care for sedation in mechanically ventilated critically ill adults, there was no difference in 90-day mortality. Dexmedetomidine may not be an ideal sedative for mechanically ventilated critically ill adults requiring deeper sedation, although its use may result in greater ventilator-free, coma-free, or delirium-free days.
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Procedural Sedation and Analgesia in the Emergency Department
Procedural sedation and analgesia (PSA) is performed in the emergency department (ED) to alleviate anxiety, decrease pain, and provide amnesia to patients undergoing painful procedures or diagnostic imaging.This article will review guidelines for performing PSA in the ED, including suggested training, preprocedural assessment, and intraprocedural monitoring.