Articles Tagged With: fetal
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Sickle Cell Disease During Pregnancy
Sickle cell disease (SCD) is the most commonly inherited autosomal recessive genetic hemoglobinopathy in the United States. People with SCD account for only 0.1% of all deliveries, but approximately 1% of maternal deaths, a 10-fold increased risk.
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The Utility of Nuchal Translucency Screening in the Era of Cell-Free Fetal DNA Testing
In this retrospective cohort study of 1,901 pregnant women between 11 weeks and 13 weeks six days of gestation who had a nuchal translucency (NT) screening for fetal aneuploidies and demonstrated NT measurements > 95th percentile, 47% of fetuses (894/1,901) had an NT between the 95th and 99th percentile and 53% (1,007/1,901) had an NT ≥ the 99th percentile. In addition, of the 43% of fetuses (814/1,901) with at least one abnormality (structural or genetic), 34% (279/814) would have been missed in the first trimester if only cell-free deoxyribonucleic acid was used for prenatal genetic screening.
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Emergencies in the Second and Third Trimesters of Pregnancy
Common emergencies specific to the second and third trimesters will be reviewed in this paper, including preterm labor, causes of antepartum bleeding in late pregnancy, and the hypertensive disorders of pregnancy. It is important to emphasize that obstetrics consultation is recommended in most emergencies that occur in the second and third trimesters prior to initiating therapies.
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Outpatient Foley Catheter for Induction of Labor in Nulliparous Women
In this randomized controlled trial among nulliparous patients with low Bishop scores, outpatient placement of a Foley catheter the day prior to scheduled admission, when compared to inpatient placement, showed a decreased mean time from admission to delivery.
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Appellate Court Affirms $10.3 Million Verdict in Cerebral Palsy Birth Suit
This case revealed multiple important issues on appeal relevant to medical malpractice cases generally. These issues can be divided into three general groups: issues about causation, issues about periodic payment, and issues about the exclusion of witnesses.
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Malaria Prophylaxis During Pregnancy
In a retrospective study of American military women involving 50 treated with atovaquone-proguanil and 156 exposed to mefloquine, no increase in risk of fetal loss or adverse infant outcomes was identified. Atovaquone-proguanil seems safe for use in pregnancy, but data are limited.
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Is RhoGAM Needed for Rh-Negative Women Experiencing First-Trimester Pregnancy Loss or Induced Abortion?
In this prospective cohort pilot study, the authors validated a flow cytometry protocol for detecting fetal red blood cells and determined that fetal red blood cell exposure in first-trimester uterine aspiration was well below the calculated threshold for maternal Rh sensitization.
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COVID-19 and Pregnancy: What Obstetricians Need to Know
While data remain limited on this particular coronavirus, extrapolation from other viruses (severe acute respiratory syndrome and Middle East respiratory syndrome), and best clinical observations and expert recommendations have led to current guidelines in care.
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Trauma in Pregnancy: A Comprehensive Overview
The authors provide a concise, comprehensive overview of the unique anatomic and physiologic features of pregnancy, as well as modifications and considerations important for the management of the pregnant trauma patient.
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The Emergency Department Management of Precipitous Delivery and Neonatal Resuscitation
Emergency department providers should be familiar with the correct procedures to manage pregnancies, births, and subsequent neonatal resuscitations when they occur unexpectedly in the ED.