Articles Tagged With: histoplasmosis
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Induction Therapy for HIV/AIDS-Related Disseminated Histoplasmosis with Single High-Dose Liposomal Amphotericin B
In a Phase II randomized clinical trial involving 118 participants in Brazil with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS)-related disseminated histoplasmosis, induction therapy with single high-dose (10 mg/kg) liposomal amphotericin B was safe and non-inferior as compared with standard dose (3 mg/kg) liposomal amphotericin B given once daily for 14 days.
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Voriconazole vs. Itraconazole for Treatment of Histoplasmosis
A retrospective cohort study found that patients treated with voriconazole had increased mortality during the first 42 days after the start of treatment compared to patients who received itraconazole.
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Histoplasmosis — Expansion of Risk Areas and Need for More Standardized Practice
Histoplasmosis is increasingly seen beyond the previous risk areas of the Ohio and Mississippi River valleys. Diagnostic and treatment practices vary widely.