Articles Tagged With: hormone
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Do Anti-Müllerian Hormone Levels Decline More Rapidly After Hysterectomy with Ovarian Conservation?
In this multi-site, community-based study, anti-Müllerian hormone levels did not decline more rapidly among patients who underwent hysterectomy with ovarian conservation compared to patients who experienced natural menopause.
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Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?
An individual-participant meta-analysis of prospective studies revealed menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.
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Estrogen Replacement: Is Long Duration of Therapy Good for the Brain?
Longer lifetime exposure to endogenous estrogen and menopausal estrogen replacement were associated with better cognitive status in older adult women. Women who initiated estrogen therapy early (within five years of the onset of menopause) showed higher cognitive test scores than those who started later.
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Menopausal Hormonal Therapy and Breast Cancer Risk: Are Old Data Relevant to Today’s Practice?
An individual-participant meta-analysis of prospective studies found menopausal hormone therapy associated with an elevation in the risk of breast cancer, with the highest risks associated with daily combined therapy.
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Estrogens Used in Hormonal Therapy
To practice as a consultant in reproductive medicine, clinicians require a strong background in hormonal therapy. In this feature, we will review the role of steroidal estrogens used in contraceptive and hormone therapy.
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Does Hormone Therapy Increase the Risk of Alzheimer’s Disease?
A large Finnish case-control study suggests that postmenopausal hormone therapy results in a 9-17% increase in the risk of Alzheimer’s disease. However, the small effect size, and likely confounding of use effect, does not provide strong evidence for a causal relationship.
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Researchers Investigate Potential Male Contraceptives
Early studies of a potential male contraceptive pill, which contains a modified testosterone that has the combined actions of an androgen and a progesterone, are underway. The experimental male oral contraceptive was the subject of a recent study to analyze its safety, tolerability, pharmacokinetics, and pharmacodynamics.
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Ripples From Original WHI Study Results Continue: Is This Appropriate?
Recommendations for menopausal hormone therapy were widely publicized and adopted following the original publication of the results of the Women’s Health Initiative and affected both initiation and continuation of estrogen therapy through at least 2013.
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Understand New Advances in Menopause Management
The Food and Drug Administration recently approved two new modalities to aid in menopause management: MenoCheck, a diagnostic tool to show a woman’s menopausal status, and Bijuva, a medication to help with hot flashes.
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Hormone Therapy and Mortality: No Overall Effect?
An evaluation of outcomes of users and nonusers of postmenopausal hormonal therapy followed longitudinally in the Danish database showed no overall difference in mortality.