Articles Tagged With: immunosuppression
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Brain Cancer and Brain Injury Drive Systemic Immunosuppression
Glioblastoma-associated immunosuppression is a significant factor associated with poor survival in this disease. Accumulating evidence suggests that mouse models of glioblastoma and other brain cancers induce systemic immunosuppression through dysregulation of a newly recognized brain-thymus axis and that targeting this pathway may promote more effective immune surveillance of these tumors.
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Vomiting and Diarrhea in Immunocompromised Patients
Patients who are immunosuppressed may exhibit subtle or atypical presentations of gastrointestinal infection, as well as complications of their underlying disease processes or treatments. Emergency physicians should maintain a high level of suspicion for life-threatening pathology and evaluate these patients using broad differentials.