In this cross-sectional analysis, pregnant women disproportionately accounted for 24-34% of influenza-associated hospitalizations among women aged 15 to 44 years, and infants younger than 2 months of age comprised the highest proportion of pertussis deaths. The reasons why pregnant women did not elect recommended immunizations included not believing they were effective, not knowing they should receive Tdap every pregnancy, and being concerned that the vaccines would harm the fetus.
Critical congenital heart disease (CCHD) is a significant cause of morbidity and mortality in children. When children with undiagnosed congenital heart disease (CHD) present acutely, the challenge of diagnosis and the importance of timely management can be daunting for any physician in an emergency setting. The children with the highest morbidity and mortality from critical congenital heart disease are infants younger than 1 year of age.
Practices vary significantly as clinicians evaluate and manage febrile infants younger than 2 months of age. A retrospective review suggests that meningitis is extremely unlikely in well-appearing babies with initial laboratory results suggestive of urinary tract infection, and that cerebrospinal fluid analysis may not be necessary.
The duration of parenteral antimicrobial therapy for bacteremic urinary tract infection in young infants varies between practitioners and centers. A retrospective review suggests that extending parenteral treatment beyond seven days does not alter outcomes.
A 12-week intervention of daily supplementation with probiotics Bifidobacterium animalis subsp. lactis (BB-12) and Lactobacillus rhamnosus (LGG) 10 billion colony-forming units produced no reduction in the number of days absent from day care in Danish infants 8 to 14 months old.
A large European multicenter study has shown that antenatal corticosteroid administration in patients at risk for imminent very early preterm birth (24 to 31 weeks) will decrease perinatal mortality and morbidity substantially, even after only three hours of exposure.
Every viral season, something gets missed. All vomiting is not acute gastroenteritis! The clinician needs to have a thorough understanding of the process of vomiting to formulate a complete differential accurately and in a timely manner. A complete history, physical exam, and targeted diagnostic testing are used to ensure an accurate diagnosis with effective management is instituted.