A retrospective cohort study from a single California hospital found the administration of probiotics to patients receiving antibiotics did not reduce the incidence of healthcare facility-onset Clostridioides difficile infection.
Influenza is an acute respiratory illness responsible for significant seasonal epidemics each year. Despite commonly being a self-limited illness, the virus causes significant morbidity and mortality. During the winter months, emergency physicians should maintain a high suspicion for influenza in patients presenting with an acute febrile respiratory illness.
Investigators evaluated 135 patients with Staphylococcus aureus bacteremia (SAB) in a prospective cohort study comparing early switch to oral linezolid to continued treatment with standard parenteral therapy (SPT). Patients with complicated SAB and osteoarticular infection were excluded. Early switch to oral therapy yielded similar outcomes to continued SPT and allowed earlier hospital discharge.