A small interventional study assessed the histological appearance of liver biopsies from patients with metabolic associated fatty liver disease (MAFLD) who completed 12-weeks of structured and supported aerobic exercise. Compared to biopsies from a nonexercising control group, the intervention arm demonstrated some reversal of histopathologic changes caused by MAFLD.
Nonalcoholic fatty liver disease (NAFLD) is the most common liver pathology worldwide and is the third leading cause of liver transplantation in the United States.This article reviews the pathogenesis, diagnosis, and natural history of NAFLD as well as known treatments and future therapies.
Metagenomic next-generation sequencing was applied to examine serum from 204 adult patients with acute liver failure (ALF). Researchers identified a potential viral etiology in eight of the 187 patients with ALF of indeterminate etiology. Potential pathogens identified in these included HSV-1, HBV, parvovirus B19, CMV, and HHV-7.