Articles Tagged With: meningitis
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Fusarium Meningitis
The presentation, management, and course of 13 patients in Texas with meningitis due to Fusarium solani occurring after spinal epidural anesthesia in Mexico are presented. At least nine have died despite multiple interventions.
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Fungal Meningitis After Epidural Injections — Again
An outbreak in Mexico of meningitis due to Fusarium solani has affected at least 79 patients who had received epidural injections; at least 35 have died.
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A Review of Meningitis
Meningitis may be a devastating disease, and early diagnosis and aggressive treatment is critical to optimize outcomes for pediatric patients. The incredible effectiveness of pediatric vaccines have changed the epidemiology and approach to pediatric meningitis. The author provides a current review of pediatric meningitis to guide the acute care clinician.
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Molecular Test Panel Use for Children with Possible Meningitis
In children thought to have meningitis, the use of a molecular test pathogen panel reduced the time to optimal antimicrobial use and reduced the duration of intravenous antibiotic use. However, there was no difference in the time to effective antimicrobial administration or the length of hospital stay between those with treatable pathogens who were and were not evaluated using molecular testing.
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Herpes Simplex Virus 2 Meningitis in Adults
The incidence of herpes simplex virus 2 meningitis in adults in Denmark over a six-year period was 0.7/100,000 population per year, with 91% of cases occurring in the absence of immunocompromise. Neurocognitive or neuropsychiatric symptoms persisted for as long as six months in approximately one-fifth of cases.
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Predictors of Therapy Outcomes for Cryptococcal Meningitis: Failure of In Vitro Susceptibility Testing, Success of Early Fungicidal Activity
Although in vitro susceptibility testing failed to have value in predicting therapeutic outcome in patients with cryptococcal meningitis, detection of a rapid decline in fungal density in cerebrospinal fluid was associated with improved outcomes in a separate study.
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Febrile Urinary Tract Infection in Young Infants — Value of Spinal Fluid Analysis
Practices vary significantly as clinicians evaluate and manage febrile infants younger than 2 months of age. A retrospective review suggests that meningitis is extremely unlikely in well-appearing babies with initial laboratory results suggestive of urinary tract infection, and that cerebrospinal fluid analysis may not be necessary.
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Infectious Meningitis: A Focused Review
The effectiveness of the current vaccine schedule has led to a significant decline in the incidence of bacterial meningitis. Delays in recognition and antibiotic administration result in increased morbidity and mortality; therefore, clinicians must maintain a high degree of vigilance for the subtle findings of meningitis, particularly in infants. Current standards for selective imaging, diagnostic testing, and empiric antibiotics are discussed.
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Listeria Monocytogenes: Maternal-fetal Infection, Bacteremia, and Meningoencephalitis
Infection with Listeria monocytogenes in pregnancy is associated with frequent fetal loss. In others, bacteremia and central nervous system infections are associated with significant mortality.
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Houston, We Have a Problem: Eosinophilic Meningitis in Children
In addition to causing eosinophilic meningitis in tropical regions, Angiostrongylus cantonensis now has been associated with chronic, otherwise unexplained fever in children in Texas.