Articles Tagged With: methylprednisolone
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Vasopressin and Steroids Increase Likelihood of Return of Spontaneous Circulation with Unclear Longer-Term Effects
In this multicenter, randomized clinical trial, the combination of vasopressin and methylprednisolone improved the rate of return of spontaneous circulation in patients with in-hospital cardiac arrest but had no significant effect on longer-term outcomes.
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COVID-19 and Steroids: Is There a Consensus on the Controversy?
A retrospective, single-center cohort study among 201 adults admitted with COVID-19 pneumonia revealed that risk factors associated with the development of acute respiratory distress syndrome (ARDS) and progression from ARDS to death included older age, neutrophilia, organ dysfunction, and coagulation derangement. Treatment with methylprednisolone may be beneficial for these patients.
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Are Steroids Indicated in the Treatment of Acute Spinal Cord Injury?
In a comprehensive review of published literature and meta-analysis of clinical trials of acute spinal cord injury treatment with high-dose steroids within eight hours of onset, the authors concluded that there is no benefit regarding neurological recovery and function and an increased risk of adverse side effects from gastrointestinal bleeding.
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Steroid Treatment Regimens for Chronic Inflammatory Demyelinating Polyneuropathy
In the United States, first-line treatment for chronic inflammatory demyelinating polyneuropathy (CIDP) is intravenous immunoglobulin (IVIG). Authors of this retrospective survey from Europe found that corticosteroid treatment had similar efficacy as IVIG and should be considered as first-line therapy for CIDP.