The opening of ATP-sensitive potassium channels by levcromakalim triggered migraine headaches in all migraineurs. In healthy volunteers, levcromakalim induced milder headaches associated with long-lasting dilation of extracerebral arteries.
Vertigo is a common and integral component of migraine and occurs with neuro-otologic abnormalities and psychiatric comorbidities. Treatment of episodic vertigo suspected to be due to vestibular migraine should mirror the multimodality treatment of migraine.
The degree of unexpectedness or “surprisal” associated with known migraine triggers is a predictor of headache attacks. Social avoidance behavior is positively correlated with headache disability, pain, and depression, but there is a negative correlation between headache pain endurance and anxiety.
In this observational, cross-sectional survey performed via an online questionnaire, researchers confirmed that alcohol consumption is a common trigger for migraine, and red wine is the type of alcohol cited as a trigger most frequently.