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Articles Tagged With: mutation

  • Lipid Pathway Dysfunction in Parkinson’s Disease

    In this large-scale study, the authors used a comprehensive untargeted lipidomic approach to determine the extent to which lipid dysregulation occurs in patients with Parkinson’s disease generally and in mutation carriers of one of the most common Parkinson’s disease risk genes, LRRK2. Further pathway analysis reveals sphingolipid metabolism, insulin signaling, and mitochondrial function as major metabolic pathways dysregulated in Parkinson’s disease.

  • Are Boosters Prolonging the Pandemic?

    Some people have raised the question of whether booster shots are unethical from a global perspective, and even counterproductive to ending the pandemic because highly mutated variants will continue to arise in unvaccinated patients.
  • Contemplating the Next Pandemic

    We have heard much about the inevitable “next pandemic” as viruses move and mutate through animals until they become infectious in humans. An example of this was published recently, revealing how an avian flu virus caused fatal infections in swans, seals, and a fox, a “terrestrial mammal” not usually vulnerable to such a virus.