One can quibble over a number of the guideline recommendations, but they provide a valuable touchstone for clinical management of patients with community-acquired pneumonia, despite the fact that so many of the recommendations are based on low- or very low-quality evidence.
Hundreds of cases of lung injury possibly related to vaping have been reported to the CDC. Evidence to date suggests the illness is a form of acute lipoid pneumonia likely related to inhalation of lipid materials.
As of Aug. 27, 2019, 215 cases of severe pulmonary disease possibly related to vaping have been reported to the CDC. Evidence to date suggests the illness is a form of acute lipoid pneumonia likely related to inhalation of lipid materials.
Coinfection with methicillin-resistant Staphylococcus aureus (MRSA) in children with influenza is associated with high fatality. Data support the addition of a second anti-MRSA antibiotic to vancomycin in severely ill children.
Tachypnea has long been considered to identify which children with acute fever and cough might benefit from antibiotic treatment, especially in resource-limited parts of the world. Now, with declining rates of vaccine-preventable infections with Haemophilus influenzae and pneumococcus, new data suggest that approximately 90% of febrile, tachypneic, coughing (but still well enough for outpatient treatment) preschoolers do fine without antibiotics.
Ultrasound has emerged as a critical tool for use at the bedside to guide both diagnosis and treatment strategies. In this article, the authors discuss cardiac arrest, congenital abnormalities, pneumothorax, pleural effusion, and pneumonia.
A meta-analysis determined that nares screening for methicillin-resistant Staphylococcus aureus (MRSA) has a high specificity and negative predictive value for MRSA pneumonia. MRSA nasal screening can be a useful tool for antimicrobial stewardship personnel to de-escalate empiric anti-MRSA therapy.
Ceftazidime-avibactam therapy was non-inferior to meropenem treatment in a double-blind, randomized trial that included patients with nosocomial pneumonia, including those with ventilator-associated pneumonia.