Postpartum emergencies may include a variety of clinical presentations, ranging from minor concerns to life-threatening emergencies. Common postpartum emergencies include pain, fever, hemorrhage, hypertension, preeclampsia, eclampsia, infection, and depression.
These authors analyzed data from a long-standing prospective cohort to study changes in prescribing habits and pregnancy outcomes following restriction on the use of valproic acid in women of child-bearing potential. Declining use of valproate and carbamazepine was associated with a decline in teratogenesis.
Cannabis use during pregnancy has become commonplace in states and countries (Canada) where it has been legalized for medical and/or recreational use. The authors of this study attempted to determine whether associations exist between self-reported prenatal cannabis use and maternal and perinatal outcomes.
This retrospective cohort study estimated that the use of CT scans has increased 3.7-fold in the United States and 2-fold in Ontario, Canada, from 1996 to 2016. Overall, 5.3% of pregnant women in the United States and 3.6% in Ontario underwent imaging with ionizing radiation.
Ectopic pregnancy has significant health consequences and represents an important cause of morbidity and mortality for women of reproductive age. Making the diagnosis of ectopic pregnancy expeditiously is critical to reduce morbidity and mortality associated with the condition.
Investigators of this well-designed, randomized, controlled trial conclusively demonstrated that progesterone supplementation does not reduce the risk of early pregnancy loss in women who experience first trimester bleeding.
The Maternal Vitamin D for Infant Growth (MDIG) trial was conducted in Bangladesh to further understand whether prenatal vitamin D with or without postpartum supplementation affects infant growth or other maternal, newborn, and infant outcomes.
In this cost-effectiveness analysis using Markov modeling, investigators found that universal antenatal screening for hepatitis C was cost-effective, with a mean incremental cost-effectiveness ratio of approximately $3,000 per quality-adjusted life years gained compared to risk-based screening.
Scientists at Brigham and Women’s Hospital have published early results of an investigative blood test designed to predict which women may be at increased risk and which ones may be at lower-than-average risk for spontaneous preterm delivery. The researchers have identified circulating microparticle proteins found in blood samples taken in the first trimester of pregnancy that may provide clues about the risk of spontaneous preterm birth.