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Articles Tagged With: prophylactic

  • BSO at Benign Hysterectomy: What Should We Be Recommending?

    In this population-based retrospective cohort study, among 44,549 adult women undergoing hysterectomy in Ontario, Canada, there was marked variation between surgeons in bilateral salpingo-oophorectomy (BSO) rates after controlling for patient age and other factors. Approximately 41% of patients had no indication for the bilateral salpingo-oophorectomy in their records.

  • Prophylaxis for Tuberculosis in Patients with Myasthenia Gravis

    In this observational study from an area with a high rate of endemic tuberculosis (TB), prophylactic treatment of TB was appropriate in those treated with high doses of prednisone and evidence of prior TB infection.

  • Prophylactic Antibiotics for Acute Aspiration

    Researchers compared outcomes in patients with aspiration pneumonitis who received prophylactic antibiotics during the first two days after macro-aspiration to patients who received only supportive care during this time. Among the 200 patients meeting the acute aspiration pneumonitis case definition, antimicrobial prophylaxis was not associated with improvement in mortality. However, patients receiving prophylactic antibiotics required more frequent escalation of antibiotics and received more days of antibiotics than those who were managed initially with supportive care alone.

  • Mefloquine: Still Effective and Still Safe for Malaria Chemoprophylaxis

    Mefloquine is known as an effective agent for malaria chemoprophylaxis. However, concerns about serious adverse effects have limited its use. Now, a careful review of data suggests that fatal outcomes related to mefloquine prophylaxis are very rare.