Articles Tagged With: prophylaxis
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Re-Evaluation of Dosing for Venous Thromboembolism Prophylaxis
Prevention of venous thromboembolism (VTE) is important for all hospitalized patients to prevent additional morbidity and costs during hospitalization. Critically ill patients in the intensive care unit (ICU) may have additional risk factors that predispose them to VTE.
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Azithromycin Prophylaxis for the Prevention of Maternal Sepsis or Death in Women Undergoing Vaginal Delivery
A single oral dose of azithromycin dramatically reduced the risk of maternal sepsis or death among women planning vaginal deliveries compared to placebo but had little effect on neonatal sepsis or mortality.
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Updates in Stress Ulcer Prophylaxis
The development of esophageal, gastric, and duodenal erosions or ulcers may increase the morbidity and mortality of critically ill patients. Stress ulcer prophylaxis can be administered pharmacologically to prevent gastrointestinal bleeding from the ulcers.
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COVID-19 Pre-Exposure Prophylaxis
The combination of tixagevimab and cilgavimab (Evusheld) was demonstrated to be effective in the prevention of symptomatic COVID-19, but much remains to be learned as SARS-CoV-2 continues to evolve.
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CGRP Antagonists: What Is Their Role in Headache Therapy?
Migraine is a highly prevalent and debilitating condition that causes significant impairment in quality of life. Preventive therapy for migraine is indicated when migraine attacks interfere with quality of life or are frequent and debilitating. The ability to prevent migraine with pharmacologic therapy has long been a goal of both patients and their physicians. The ideal preventive (prophylactic) migraine treatment should be effective, safe, and well tolerated, with few or no contraindications, few or no drug interactions, safety in pregnancy and breastfeeding, and dosed in a manner to ease adherence.
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AAP Recommends Routine HIV Screening, Prevention for All Teens, At-Risk Youth
The organization advises pediatricians to create safe spaces that allow frank discussions of sensitive topics.
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Treatment of Seizures After Spontaneous Intracerebral Hemorrhage
The reported incidence of post-stroke seizures varies and appears to have a higher incidence following hemorrhagic stroke. Post-stroke seizures have been associated with a greater length of hospitalization, increased mortality, and complications. This study compared four seizure prophylaxis strategies to determine the greatest net benefit for patients with spontaneous intracerebral hemorrhage. There was a better outcome with short-term antiepileptic medication use compared to long-term use.
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COVID-19: Effective Post-Exposure Prophylaxis
Subcutaneous administration of a combination of anti-SARS-COV-2 antibodies effectively prevented COVID-19 in most household contacts of cases.
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Effect of Stress Ulcer Prophylaxis Choice on Mortality in Mechanically Ventilated Adults
Proton pump inhibitors reduce the risk of clinically important bleeding, but they may have no effect on the risk of 90-day mortality compared to histamine-2 receptor antagonists.
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Infections and Prophylaxis in Pediatric Trauma Patients
The emergency medicine physician serves a critical role for trauma and surgical patients. Early recognition of infections and understanding the indications for prophylaxis are critical for management of pediatric trauma patients. The authors explore the most common etiologic agents by body system and prophylactic and therapeutic strategies.