Articles Tagged With: resistance
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Resistance of SARS-CoV-2 Variants to Monoclonal Antibodies
Prevalent SARS-CoV-2 variants are increasingly resistant to therapeutic and prophylactic monoclonal antibodies but remain susceptible to Paxlovid, remdesivir, and molnupiravir.
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Initial Antibiotic Choice for Neonatal Sepsis in Low- and Middle-Income Countries
Gram-negative rods are responsible for most neonatal sepsis in low- and middle-income countries. Ampicillin-gentamicin usually has been recommended for presumptive treatment, pending bacteriology results (when such tests are available). The results of a multinational study in Africa and Asia suggest resistance to standard therapy is widespread and that ceftazidime-amikacin might be a better option.
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Infectious Disease Alert Updates
A Reservoir of Pharyngeal GC; Difficult-to-Treat vs. Standard Multidrug Resistance
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Ceftriaxone-Resistant Gonorrhea Has Arrived in the United States
A man in Las Vegas with gonorrhea was infected with the first ceftriaxone-resistant strain of Neisseria gonorrhoeae identified in the United States.
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HHS Releases Latest Iteration of Antibiotic Resistance Action Plan
The new plan includes details about stronger and more evidence-based activities that have reduced antibiotic resistance, such as optimizing the use of antibiotics in human and animal health settings, that public health officials can lean on to drive progress.
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Antibiotics for Traveler’s Diarrhea
International travel carries a risk of colonization by antimicrobial-resistant intestinal flora. The use of a quinolone, but not a macrolide, during travel further increases the risk of acquisition of extended-spectrum beta-lactamase-producing Enterobacteriaceae.
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HHS Releases Latest Iteration of Antibiotic Resistance Action Plan
New edition builds on similar plan that preceded it, success hinges on proper resource allocation.
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Antibiotic Stewardship: Who’s Responsible?
A joint Pew/AMA survey about resistance and prescribing habits sheds light on provider attitudes and the work ahead.
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Monotherapy of Pseudomonas aeruginosa Bacteremia — Which β-Lactam Antibiotic Is Best?
No significant difference in the mortality of patients with Pseudomonas aeruginosa bacteremia was seen regardless of treatment with a carbapenem, ceftazidime, or piperacillin-tazobactam. However, the emergence of resistance occurred significantly more frequently in those treated with a carbapenem — largely related to imipenem use.
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Candida auris Resistant to Azole Antifungals, Amphotericin B, and Echinocandins
Infection with Candida auris resistant to azole antifungals, amphotericin B, and echinocandins was identified in three patients in New York. Resistance to echinocandins was first detected after the patients had received an echinocandin as treatment.